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Correlation of EGFR expression, gene copy number and clinicopathological status in NSCLC

BACKGROUND: Epidermal Growth Factor Receptor (EGFR) targeting therapies are currently of great relevance for the treatment of lung cancer. For this reason, in addition to mutational analysis immunohistochemistry (IHC) of EGFR in lung cancer has been discussed for the decision making of according the...

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Detalles Bibliográficos
Autores principales: Gaber, Rania, Watermann, Iris, Kugler, Christian, Reinmuth, Nils, Huber, Rudolf M, Schnabel, Philipp A, Vollmer, Ekkehard, Reck, Martin, Goldmann, Torsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176848/
https://www.ncbi.nlm.nih.gov/pubmed/25227424
http://dx.doi.org/10.1186/s13000-014-0165-0