PIN3 duplication may be partially responsible for TP53 haploinsufficiency

BACKGROUND: Previously we have suggested that cancer cells develop a mechanism(s) which allows for either: silencing of the wild-type TP53 transcription, degradation of the wild-type TP53 mRNA, or selective overproduction of the mutated TP53 mRNA, which is the subject of this article. Sequencing of...

Descripción completa

Detalles Bibliográficos
Autores principales: Winiecka-Klimek, Marta, Szybka, Malgorzata, Rieske, Piotr, Piaskowski, Sylwester, Bienkowski, Michal, Walczak, Maciej, Pacholczyk, Marcin, Rostkowski, Michal, Zieba, Jolanta, Banaszczyk, Mateusz, Hulas-Bigoszewska, Krystyna, Peciak, Joanna, Pawliczak, Rafal, Stoczynska-Fidelus, Ewelina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176858/
https://www.ncbi.nlm.nih.gov/pubmed/25223755
http://dx.doi.org/10.1186/1471-2407-14-669

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176858/
https://www.ncbi.nlm.nih.gov/pubmed/25223755
http://dx.doi.org/10.1186/1471-2407-14-669

Ejemplares similares