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PIN3 duplication may be partially responsible for TP53 haploinsufficiency
BACKGROUND: Previously we have suggested that cancer cells develop a mechanism(s) which allows for either: silencing of the wild-type TP53 transcription, degradation of the wild-type TP53 mRNA, or selective overproduction of the mutated TP53 mRNA, which is the subject of this article. Sequencing of...
Autores principales: | Winiecka-Klimek, Marta, Szybka, Malgorzata, Rieske, Piotr, Piaskowski, Sylwester, Bienkowski, Michal, Walczak, Maciej, Pacholczyk, Marcin, Rostkowski, Michal, Zieba, Jolanta, Banaszczyk, Mateusz, Hulas-Bigoszewska, Krystyna, Peciak, Joanna, Pawliczak, Rafal, Stoczynska-Fidelus, Ewelina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176858/ https://www.ncbi.nlm.nih.gov/pubmed/25223755 http://dx.doi.org/10.1186/1471-2407-14-669 |
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