Optimizations of SiRNA Design for the Activation of Gene Transcription by Targeting the TATA-Box Motif

Small interfering RNAs (siRNAs) are widely used to repress gene expression by targeting mRNAs. Some reports reveal that siRNAs can also activate or inhibit gene expression through targeting the gene promoters. Our group has found that microRNAs (miRNAs) could activate gene transcription via interact...

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Detalles Bibliográficos
Autores principales: Fan, Miaomiao, Zhang, Yijun, Huang, Zhuoqiong, Liu, Jun, Guo, Xuemin, Zhang, Hui, Luo, Haihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176967/
https://www.ncbi.nlm.nih.gov/pubmed/25250958
http://dx.doi.org/10.1371/journal.pone.0108253

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176967/
https://www.ncbi.nlm.nih.gov/pubmed/25250958
http://dx.doi.org/10.1371/journal.pone.0108253

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