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Neurotrophins regulate ApoER2 proteolysis through activation of the Trk signaling pathway

BACKGROUND: ApoER2 and the neurotrophin receptors Trk and p75(NTR) are expressed in the CNS and regulate key functional aspects of neurons, including development, survival, and neuronal function. It is known that both ApoER2 and p75(NTR) are processed by metalloproteinases, followed by regulated int...

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Detalles Bibliográficos
Autores principales: Larios, Jorge A, Jausoro, Ignacio, Benitez, Maria-Luisa, Bronfman, Francisca C, Marzolo, Maria-Paz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177048/
https://www.ncbi.nlm.nih.gov/pubmed/25233900
http://dx.doi.org/10.1186/1471-2202-15-108