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Neurotrophins regulate ApoER2 proteolysis through activation of the Trk signaling pathway
BACKGROUND: ApoER2 and the neurotrophin receptors Trk and p75(NTR) are expressed in the CNS and regulate key functional aspects of neurons, including development, survival, and neuronal function. It is known that both ApoER2 and p75(NTR) are processed by metalloproteinases, followed by regulated int...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177048/ https://www.ncbi.nlm.nih.gov/pubmed/25233900 http://dx.doi.org/10.1186/1471-2202-15-108 |