Nuclear localized Influenza nucleoprotein N-terminal deletion mutant is deficient in functional vRNP formation

BACKGROUND: The influenza RNA dependent RNA polymerase synthesizes viral RNA in the nucleus as functional viral ribonucleoprotein (vRNP) complexes with RNA and nucleoprotein (NP). The N-terminus of NP contains an unconventional nuclear localization signal (NLS) important for initial vRNP nuclear loc...

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Detalles Bibliográficos
Autores principales: Sanchez, Abel, Guerrero-Juarez, Christian F, Ramirez, Jose, Newcomb, Laura L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177073/
https://www.ncbi.nlm.nih.gov/pubmed/25174360
http://dx.doi.org/10.1186/1743-422X-11-155

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177073/
https://www.ncbi.nlm.nih.gov/pubmed/25174360
http://dx.doi.org/10.1186/1743-422X-11-155

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