On the Perplexingly Low Rate of Transport of IgG2 across the Human Placenta

The neonatal receptor, FcRn, mediates both serum half–life extension as well as active transport of maternal IgG to the fetus during pregnancy. Therefore, transport efficiency and half-life go hand-in-hand. However, while the half-life of the human IgG2 subclass is comparable to IgG1, the placental...

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Detalles Bibliográficos
Autores principales: Einarsdottir, Helga K., Stapleton, Nigel M., Scherjon, Sicco, Andersen, Jan Terje, Rispens, Theo, van der Schoot, C. Ellen, Vidarsson, Gestur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177109/
https://www.ncbi.nlm.nih.gov/pubmed/25251461
http://dx.doi.org/10.1371/journal.pone.0108319

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177109/
https://www.ncbi.nlm.nih.gov/pubmed/25251461
http://dx.doi.org/10.1371/journal.pone.0108319

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