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Defining Differentially Methylated Regions Specific for the Acquisition of Pluripotency and Maintenance in Human Pluripotent Stem Cells via Microarray

BACKGROUND: Epigenetic regulation is critical for the maintenance of human pluripotent stem cells. It has been shown that pluripotent stem cells, such as embryonic stem cells and induced pluripotent stem cells, appear to have a hypermethylated status compared with differentiated cells. However, the...

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Detalles Bibliográficos
Autores principales: He, WenYin, Kang, XiangJin, Du, HongZi, Song, Bing, Lu, ZhenYu, Huang, Yuling, Wang, Ding, Sun, Xiaofang, Yu, Yang, Fan, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177110/
https://www.ncbi.nlm.nih.gov/pubmed/25250679
http://dx.doi.org/10.1371/journal.pone.0108350