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Targeting Mitochondria by Zn(II)N-Alkylpyridylporphyrins: The Impact of Compound Sub-Mitochondrial Partition on Cell Respiration and Overall Photodynamic Efficacy

Mitochondria play a key role in aerobic ATP production and redox control. They harness crucial metabolic pathways and control cell death mechanisms, properties that make these organelles essential for survival of most eukaryotic cells. Cancer cells have altered cell death pathways and typically show...

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Detalles Bibliográficos
Autores principales: Odeh, Ahmad M., Craik, James D., Ezzeddine, Rima, Tovmasyan, Artak, Batinic-Haberle, Ines, Benov, Ludmil T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177117/
https://www.ncbi.nlm.nih.gov/pubmed/25250732
http://dx.doi.org/10.1371/journal.pone.0108238