Cargando…

Survivin expression promotes VEGF-induced tumor angiogenesis via PI3K/Akt enhanced β-catenin/Tcf-Lef dependent transcription

Early in cancer development, tumour cells express vascular endothelial growth factor (VEGF), a secreted molecule that is important in all stages of angiogenesis, an essential process that provides nutrients and oxygen to the nascent tumor and thereby enhances tumor-cell survival and facilitates grow...

Descripción completa

Detalles Bibliográficos
Autores principales: Fernández, Jaime G, Rodríguez, Diego A, Valenzuela, Manuel, Calderon, Claudia, Urzúa, Ulises, Munroe, David, Rosas, Carlos, Lemus, David, Díaz, Natalia, Wright, Mathew C, Leyton, Lisette, Tapia, Julio C, Quest, Andrew FG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177250/
https://www.ncbi.nlm.nih.gov/pubmed/25204429
http://dx.doi.org/10.1186/1476-4598-13-209