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G9a co-suppresses LINE1 elements in spermatogonia

BACKGROUND: Repression of retrotransposons is essential for genome integrity and the development of germ cells. Among retrotransposons, the establishment of CpG DNA methylation and epigenetic silencing of LINE1 (L1) elements and the intracisternal A particle (IAP) endogenous retrovirus (ERV) is depe...

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Detalles Bibliográficos
Autores principales: Di Giacomo, Monica, Comazzetto, Stefano, Sampath, Srihari C, Sampath, Srinath C, O’Carroll, Dónal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177377/
https://www.ncbi.nlm.nih.gov/pubmed/25276231
http://dx.doi.org/10.1186/1756-8935-7-24