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G9a co-suppresses LINE1 elements in spermatogonia
BACKGROUND: Repression of retrotransposons is essential for genome integrity and the development of germ cells. Among retrotransposons, the establishment of CpG DNA methylation and epigenetic silencing of LINE1 (L1) elements and the intracisternal A particle (IAP) endogenous retrovirus (ERV) is depe...
Autores principales: | Di Giacomo, Monica, Comazzetto, Stefano, Sampath, Srihari C, Sampath, Srinath C, O’Carroll, Dónal |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177377/ https://www.ncbi.nlm.nih.gov/pubmed/25276231 http://dx.doi.org/10.1186/1756-8935-7-24 |
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