Mir-34a Mimics Are Potential Therapeutic Agents for p53-Mutated and Chemo-Resistant Brain Tumour Cells

Chemotherapeutic drug resistance and relapse remains a major challenge for paediatric (medulloblastoma) and adult (glioblastoma) brain tumour treatment. Medulloblastoma tumours and cell lines with mutations in the p53 signalling pathway have been shown to be specifically insensitive to DNA damaging...

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Detalles Bibliográficos
Autores principales: Fan, Yuen Ngan, Meley, Daniel, Pizer, Barry, Sée, Violaine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177398/
https://www.ncbi.nlm.nih.gov/pubmed/25250818
http://dx.doi.org/10.1371/journal.pone.0108514

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177398/
https://www.ncbi.nlm.nih.gov/pubmed/25250818
http://dx.doi.org/10.1371/journal.pone.0108514

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