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TLR2 stimulation induces cardiac inflammation but not cardiac depression in vivo

BACKGROUND: Bacteria such as Staphylococcus aureus induce myocardial dysfunction in vivo. To rectify conflicting evidence about the role of TLR2 signaling and cardiac dysfunction, we hypothesized that the specific TLR2 agonist purified lipoteichoic acid (LTA) from S. aureus contributes to cardiac dy...

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Detalles Bibliográficos
Autores principales: Boehm, Olaf, Knuefermann, Pascal, Plueck, Johannes, Schwederski, Markus, Ehrentraut, Heidi, Kebir, Sied, Lohner, Ralph, Velten, Markus, Morath, Siegfried, Koch, Alexander, Zacharowski, Kai, Grohé, Christian, Hoeft, Andreas, Baumgarten, Georg, Meyer, Rainer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177531/
https://www.ncbi.nlm.nih.gov/pubmed/24171786
http://dx.doi.org/10.1186/1476-9255-10-33