Cargando…
QSAR analysis on tacrine-related acetylcholinesterase inhibitors
BACKGROUND: The evaluation of the clinical effects of Tacrine has shown efficacy in delaying the deterioration of the symptoms of Alzheimer’s disease, while confirming the adverse events consisting mainly in the elevated liver transaminase levels. The study of tacrine analogs presents a continuous i...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177578/ https://www.ncbi.nlm.nih.gov/pubmed/25239202 http://dx.doi.org/10.1186/s12929-014-0084-0 |