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QSAR analysis on tacrine-related acetylcholinesterase inhibitors

BACKGROUND: The evaluation of the clinical effects of Tacrine has shown efficacy in delaying the deterioration of the symptoms of Alzheimer’s disease, while confirming the adverse events consisting mainly in the elevated liver transaminase levels. The study of tacrine analogs presents a continuous i...

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Detalles Bibliográficos
Autores principales:	Wong, Kai Y, Mercader, Andrew G, Saavedra, Laura M, Honarparvar, Bahareh, Romanelli, Gustavo P, Duchowicz, Pablo R
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177578/ https://www.ncbi.nlm.nih.gov/pubmed/25239202 http://dx.doi.org/10.1186/s12929-014-0084-0

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