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Correcting for multiple-testing in multi-arm trials: is it necessary and is it done?

BACKGROUND: Multi-arm trials enable the evaluation of multiple treatments within a single trial. They provide a way of substantially increasing the efficiency of the clinical development process. However, since multi-arm trials test multiple hypotheses, some regulators require that a statistical cor...

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Detalles Bibliográficos
Autores principales: Wason, James M S, Stecher, Lynne, Mander, Adrian P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177585/
https://www.ncbi.nlm.nih.gov/pubmed/25230772
http://dx.doi.org/10.1186/1745-6215-15-364