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ECMIS: computational approach for the identification of hotspots at protein-protein interfaces

BACKGROUND: Various methods have been developed to computationally predict hotspot residues at novel protein-protein interfaces. However, there are various challenges in obtaining accurate prediction. We have developed a novel method which uses different aspects of protein structure and sequence spa...

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Detalles Bibliográficos
Autores principales: Shingate, Prashant, Manoharan, Malini, Sukhwal, Anshul, Sowdhamini, Ramanathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177600/
https://www.ncbi.nlm.nih.gov/pubmed/25228146
http://dx.doi.org/10.1186/1471-2105-15-303