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Whole gene expression profile in blood reveals multiple pathways deregulation in R6/2 mouse model
BACKGROUND: Huntington Disease (HD) is a progressive neurological disorder, with pathological manifestations in brain areas and in periphery caused by the ubiquitous expression of mutant Huntingtin protein. Transcriptional dysregulation is considered a key molecular mechanism responsible of HD patho...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177605/ https://www.ncbi.nlm.nih.gov/pubmed/24252798 http://dx.doi.org/10.1186/2050-7771-1-28 |