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Molecular signatures of chronic myeloid leukemia stem cells

BCR-ABL tyrosine kinase inhibitors (TKIs) are effective in controlling Philadelphia-positive (Ph(+)) chronic myeloid leukemia (CML) are unlikely to cure the disease because TKIs are unable to eradicate leukemia stem cells (LSCs) responsible for the disease relapse even after tyrosine kinase inhibiti...

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Detalles Bibliográficos
Autores principales: Chen, Yaoyu, Li, Shaoguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177606/
https://www.ncbi.nlm.nih.gov/pubmed/24252550
http://dx.doi.org/10.1186/2050-7771-1-21