Dopamine Signaling Leads to Loss of Polycomb Repression and Aberrant Gene Activation in Experimental Parkinsonism

Polycomb group (PcG) proteins bind to and repress genes in embryonic stem cells through lineage commitment to the terminal differentiated state. PcG repressed genes are commonly characterized by the presence of the epigenetic histone mark H3K27me3, catalyzed by the Polycomb repressive complex 2. Her...

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Detalles Bibliográficos
Autores principales: Södersten, Erik, Feyder, Michael, Lerdrup, Mads, Gomes, Ana-Luisa, Kryh, Hanna, Spigolon, Giada, Caboche, Jocelyne, Fisone, Gilberto, Hansen, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177666/
https://www.ncbi.nlm.nih.gov/pubmed/25254549
http://dx.doi.org/10.1371/journal.pgen.1004574

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177666/
https://www.ncbi.nlm.nih.gov/pubmed/25254549
http://dx.doi.org/10.1371/journal.pgen.1004574

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