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GLD-4-Mediated Translational Activation Regulates the Size of the Proliferative Germ Cell Pool in the Adult C. elegans Germ Line

To avoid organ dysfunction as a consequence of tissue diminution or tumorous growth, a tight balance between cell proliferation and differentiation is maintained in metazoans. However, cell-intrinsic gene expression mechanisms controlling adult tissue homeostasis remain poorly understood. By focusin...

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Detalles Bibliográficos
Autores principales: Millonigg, Sophia, Minasaki, Ryuji, Nousch, Marco, Eckmann, Christian R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177745/
https://www.ncbi.nlm.nih.gov/pubmed/25254367
http://dx.doi.org/10.1371/journal.pgen.1004647