Nipbl and Mediator Cooperatively Regulate Gene Expression to Control Limb Development

Haploinsufficiency for Nipbl, a cohesin loading protein, causes Cornelia de Lange Syndrome (CdLS), the most common “cohesinopathy”. It has been proposed that the effects of Nipbl-haploinsufficiency result from disruption of long-range communication between DNA elements. Here we use zebrafish and mou...

Descripción completa

Detalles Bibliográficos
Autores principales: Muto, Akihiko, Ikeda, Shingo, Lopez-Burks, Martha E., Kikuchi, Yutaka, Calof, Anne L., Lander, Arthur D., Schilling, Thomas F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177752/
https://www.ncbi.nlm.nih.gov/pubmed/25255084
http://dx.doi.org/10.1371/journal.pgen.1004671

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177752/
https://www.ncbi.nlm.nih.gov/pubmed/25255084
http://dx.doi.org/10.1371/journal.pgen.1004671

Ejemplares similares