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Nipbl and Mediator Cooperatively Regulate Gene Expression to Control Limb Development

Haploinsufficiency for Nipbl, a cohesin loading protein, causes Cornelia de Lange Syndrome (CdLS), the most common “cohesinopathy”. It has been proposed that the effects of Nipbl-haploinsufficiency result from disruption of long-range communication between DNA elements. Here we use zebrafish and mou...

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Detalles Bibliográficos
Autores principales:	Muto, Akihiko, Ikeda, Shingo, Lopez-Burks, Martha E., Kikuchi, Yutaka, Calof, Anne L., Lander, Arthur D., Schilling, Thomas F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177752/ https://www.ncbi.nlm.nih.gov/pubmed/25255084 http://dx.doi.org/10.1371/journal.pgen.1004671

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