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Entecavir combined with furin inhibitor simultaneously reduces hepatitis B virus replication and e antigen secretion

BACKGROUND: The antiviral therapy of chronic hepatitis B virus (HBV) infection pursues the dual goals, virological response (undetectable serum HBV DNA) and hepatitis B e antigen (HBeAg) serological response (serum HBeAg loss/seroconversion). It is relatively difficult, however, to realize the serol...

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Detalles Bibliográficos
Autores principales: Yang, Hui Y, Zheng, Nai Q, Li, Dong M, Gu, Lin, Peng, Xiao M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177756/
https://www.ncbi.nlm.nih.gov/pubmed/25224377
http://dx.doi.org/10.1186/1743-422X-11-165