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Immune Modulatory Effects of IL-22 on Allergen-Induced Pulmonary Inflammation

IL-22 is a Th17/Th22 cytokine that is increased in asthma. However, recent animal studies showed controversial findings in the effects of IL-22 in allergic asthma. To determine the role of IL-22 in ovalbumin-induced allergic inflammation we generated inducible lung-specific IL-22 transgenic mice. Tr...

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Detalles Bibliográficos
Autores principales: Fang, Ping, Zhou, Li, Zhou, Yuqi, Kolls, Jay K., Zheng, Tao, Zhu, Zhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177833/
https://www.ncbi.nlm.nih.gov/pubmed/25254361
http://dx.doi.org/10.1371/journal.pone.0107454