Deazaneplanocin A Is a Promising Drug to Kill Multiple Myeloma Cells in Their Niche

Tumoral plasma cells has retained stemness features and in particular, a polycomb-silenced gene expression signature. Therefore, epigenetic therapy could be a mean to fight for multiple myeloma (MM), still an incurable pathology. Deazaneplanocin A (DZNep), a S-adenosyl-L-homocysteine hydrolase inhib...

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Detalles Bibliográficos
Autores principales: Gaudichon, Jérémie, Milano, Francesco, Cahu, Julie, DaCosta, Lætitia, Martens, Anton C., Renoir, Jack-Michel, Sola, Brigitte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177844/
https://www.ncbi.nlm.nih.gov/pubmed/25255316
http://dx.doi.org/10.1371/journal.pone.0107009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177844/
https://www.ncbi.nlm.nih.gov/pubmed/25255316
http://dx.doi.org/10.1371/journal.pone.0107009

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