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Cathepsin B in Antigen-Presenting Cells Controls Mediators of the Th1 Immune Response during Leishmania major Infection

Resistance and susceptibility to Leishmania major infection in the murine model is determined by the capacity of the host to mount either a protective Th1 response or a Th2 response associated with disease progression. Previous reports involving the use of cysteine cathepsin inhibitors indicated tha...

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Detalles Bibliográficos
Autores principales: Gonzalez-Leal, Iris J., Röger, Bianca, Schwarz, Angela, Schirmeister, Tanja, Reinheckel, Thomas, Lutz, Manfred B., Moll, Heidrun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177854/
https://www.ncbi.nlm.nih.gov/pubmed/25255101
http://dx.doi.org/10.1371/journal.pntd.0003194