Characterization of a Novel Anti-Cancer Compound for Astrocytomas

The standard chemotherapy for brain tumors is temozolomide (TMZ), however, as many as 50% of brain tumors are reportedly TMZ resistant leaving patients without a chemotherapeutic option. We performed serial screening of TMZ resistant astrocytoma cell lines, and identified compounds that are cytotoxi...

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Detalles Bibliográficos
Autores principales: Lee, Sang Y., Slagle-Webb, Becky, Rizk, Elias, Patel, Akshal, Miller, Patti A., Sung, Shen-Shu, Connor, James R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177861/
https://www.ncbi.nlm.nih.gov/pubmed/25255031
http://dx.doi.org/10.1371/journal.pone.0108166

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177861/
https://www.ncbi.nlm.nih.gov/pubmed/25255031
http://dx.doi.org/10.1371/journal.pone.0108166

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