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RNAi Dynamics in Juvenile Fasciola spp. Liver Flukes Reveals the Persistence of Gene Silencing In Vitro

BACKGROUND: Fasciola spp. liver fluke cause pernicious disease in humans and animals. Whilst current control is unsustainable due to anthelmintic resistance, gene silencing (RNA interference, RNAi) has the potential to contribute to functional validation of new therapeutic targets. The susceptibilit...

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Detalles Bibliográficos
Autores principales: McVeigh, Paul, McCammick, Erin M., McCusker, Paul, Morphew, Russell M., Mousley, Angela, Abidi, Abbas, Saifullah, Khalid M., Muthusamy, Raman, Gopalakrishnan, Ravikumar, Spithill, Terry W., Dalton, John P., Brophy, Peter M., Marks, Nikki J., Maule, Aaron G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177864/
https://www.ncbi.nlm.nih.gov/pubmed/25254508
http://dx.doi.org/10.1371/journal.pntd.0003185