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Human Eosinophils Express the High Affinity IgE Receptor, FcεRI, in Bullous Pemphigoid

Bullous pemphigoid (BP) is an autoimmune blistering disease mediated by autoantibodies targeting BP180 (type XVII collagen). Patient sera and tissues typically have IgG and IgE autoantibodies and elevated eosinophil numbers. Although the pathogenicity of the IgE autoantibodies is established in BP,...

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Detalles Bibliográficos
Autores principales: Messingham, Kelly N., Holahan, Heather M., Frydman, Alexandra S., Fullenkamp, Colleen, Srikantha, Rupasree, Fairley, Janet A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177878/
https://www.ncbi.nlm.nih.gov/pubmed/25255430
http://dx.doi.org/10.1371/journal.pone.0107725