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Clinical Validation and Implications of Dried Blood Spot Sampling of Carbamazepine, Valproic Acid and Phenytoin in Patients with Epilepsy

To facilitate therapeutic monitoring of antiepileptic drugs (AEDs) by healthcare professionals for patients with epilepsy (PWE), we applied a GC-MS assay to measure three AEDs: carbamazepine (CBZ), phenytoin (PHT) and valproic acid (VPA) levels concurrently in one dried blood spot (DBS), and validat...

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Detalles Bibliográficos
Autores principales: Kong, Sing Teang, Lim, Shih-Hui, Lee, Wee Beng, Kumar, Pasikanthi Kishore, Wang, Hwee Yi Stella, Ng, Yan Lam Shannon, Wong, Pei Shieen, Ho, Paul C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177879/
https://www.ncbi.nlm.nih.gov/pubmed/25255292
http://dx.doi.org/10.1371/journal.pone.0108190