Strong Type 1, but Impaired Type 2, Immune Responses Contribute to Orientia tsutsugamushi-Induced Pathology in Mice

Scrub typhus is a neglected, but important, tropical disease, which puts one-third of the world's population at risk. The disease is caused by Orientia tsutsugamushi, an obligately intracellular Gram-negative bacterium. Dysregulation in immune responses is known to contribute to disease pathoge...

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Detalles Bibliográficos
Autores principales: Soong, Lynn, Wang, Hui, Shelite, Thomas R., Liang, Yuejin, Mendell, Nicole L., Sun, Jiaren, Gong, Bin, Valbuena, Gustavo A., Bouyer, Donald H., Walker, David H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177881/
https://www.ncbi.nlm.nih.gov/pubmed/25254971
http://dx.doi.org/10.1371/journal.pntd.0003191

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177881/
https://www.ncbi.nlm.nih.gov/pubmed/25254971
http://dx.doi.org/10.1371/journal.pntd.0003191

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