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Hybrid and Rogue Kinases Encoded in the Genomes of Model Eukaryotes

The highly modular nature of protein kinases generates diverse functional roles mediated by evolutionary events such as domain recombination, insertion and deletion of domains. Usually domain architecture of a kinase is related to the subfamily to which the kinase catalytic domain belongs. However o...

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Detalles Bibliográficos
Autores principales: Rakshambikai, Ramaswamy, Gnanavel, Mutharasu, Srinivasan, Narayanaswamy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177888/
https://www.ncbi.nlm.nih.gov/pubmed/25255313
http://dx.doi.org/10.1371/journal.pone.0107956