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RNF26 Temporally Regulates Virus-Triggered Type I Interferon Induction by Two Distinct Mechanisms

Viral infection triggers induction of type I interferons (IFNs), which are critical mediators of innate antiviral immune response. Mediator of IRF3 activation (MITA, also called STING) is an adapter essential for virus-triggered IFN induction pathways. How post-translational modifications regulate t...

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Detalles Bibliográficos
Autores principales: Qin, Yue, Zhou, Mao-Tian, Hu, Ming-Ming, Hu, Yun-Hong, Zhang, Jing, Guo, Lin, Zhong, Bo, Shu, Hong-Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177927/
https://www.ncbi.nlm.nih.gov/pubmed/25254379
http://dx.doi.org/10.1371/journal.ppat.1004358