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Evaluation of Neuronal Apoptosis Precursors in an Experimental Model of Acute Normovolemic Hemodilution

BACKGROUND: The effects of acute anemia on neuronal cells and the safe limits of hematocrit are not well established. The objective of this study was to evaluate neuronal pro- and anti-apoptotic Bax and Bcl-x proteins, caspase-3 and -9 activity, and DNA fragmentation after acute normovolemic hemodil...

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Detalles Bibliográficos
Autores principales: Frazilio, Fabrício O., Otsuki, Denise Aya, Noel-Morgan, Jessica, Maximino, Jessica Ruivo, Oliveira, Gabriela Pintar, Chadi, Gerson, Auler, Jose Otavio Costa, Fantoni, Denise Tabacchi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177928/
https://www.ncbi.nlm.nih.gov/pubmed/25254661
http://dx.doi.org/10.1371/journal.pone.0108366