Myelin Basic Protein Induces Neuron-Specific Toxicity by Directly Damaging the Neuronal Plasma Membrane

The central nervous system (CNS) insults may cause massive demyelination and lead to the release of myelin-associated proteins including its major component myelin basic protein (MBP). MBP is reported to induce glial activation but its effect on neurons is still little known. Here we found that MBP...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Jie, Sun, Xin, Zheng, Sixin, Liu, Xiao, Jin, Jinghua, Ren, Yi, Luo, Jianhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177931/
https://www.ncbi.nlm.nih.gov/pubmed/25255088
http://dx.doi.org/10.1371/journal.pone.0108646

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177931/
https://www.ncbi.nlm.nih.gov/pubmed/25255088
http://dx.doi.org/10.1371/journal.pone.0108646

Ejemplares similares