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Myelin Basic Protein Induces Neuron-Specific Toxicity by Directly Damaging the Neuronal Plasma Membrane
The central nervous system (CNS) insults may cause massive demyelination and lead to the release of myelin-associated proteins including its major component myelin basic protein (MBP). MBP is reported to induce glial activation but its effect on neurons is still little known. Here we found that MBP...
Autores principales: | Zhang, Jie, Sun, Xin, Zheng, Sixin, Liu, Xiao, Jin, Jinghua, Ren, Yi, Luo, Jianhong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177931/ https://www.ncbi.nlm.nih.gov/pubmed/25255088 http://dx.doi.org/10.1371/journal.pone.0108646 |
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