Trehalose Improves Human Fibroblast Deficits in a New CHIP-Mutation Related Ataxia

In this work we investigate the role of CHIP in a new CHIP-mutation related ataxia and the therapeutic potential of trehalose. The patient's fibroblasts with a new form of hereditary ataxia, related to STUB1 gene (CHIP) mutations, and three age and sex-matched controls were treated with epoxomi...

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Detalles Bibliográficos
Autores principales: Casarejos, Maria Jose, Perucho, Juan, López-Sendón, Jose Luis, García de Yébenes, Justo, Bettencourt, Conceição, Gómez, Ana, Ruiz, Carolina, Heutink, Peter, Rizzu, Patrizia, Mena, Maria Angeles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4178022/
https://www.ncbi.nlm.nih.gov/pubmed/25259530
http://dx.doi.org/10.1371/journal.pone.0106931

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4178022/
https://www.ncbi.nlm.nih.gov/pubmed/25259530
http://dx.doi.org/10.1371/journal.pone.0106931

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