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Different IVIG Glycoforms Affect In Vitro Inhibition of Anti-Ganglioside Antibody-Mediated Complement Deposition

Intravenous immunoglobulin (IVIG) is the first line treatment for Guillain–Barré syndrome and multifocal motor neuropathy, which are caused by anti-ganglioside antibody-mediated complement-dependent cytotoxicity. IVIG has many potential mechanisms of action, and sialylation of the IgG Fc portion rep...

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Detalles Bibliográficos
Autores principales: Sudo, Makoto, Yamaguchi, Yoshiki, Späth, Peter J., Matsumoto-Morita, Kana, Ong, Benjamin K., Shahrizaila, Nortina, Yuki, Nobuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4178036/
https://www.ncbi.nlm.nih.gov/pubmed/25259950
http://dx.doi.org/10.1371/journal.pone.0107772