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Multivariate Dimensionality Reduction Approaches to Identify Gene-Gene and Gene-Environment Interactions Underlying Multiple Complex Traits

The elusive but ubiquitous multifactor interactions represent a stumbling block that urgently needs to be removed in searching for determinants involved in human complex diseases. The dimensionality reduction approaches are a promising tool for this task. Many complex diseases exhibit composite synd...

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Detalles Bibliográficos
Autores principales: Xu, Hai-Ming, Sun, Xi-Wei, Qi, Ting, Lin, Wan-Yu, Liu, Nianjun, Lou, Xiang-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4178067/
https://www.ncbi.nlm.nih.gov/pubmed/25259584
http://dx.doi.org/10.1371/journal.pone.0108103