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Direct Proof of the In Vivo Pathogenic Role of the AChR Autoantibodies from Myasthenia Gravis Patients

Several studies have suggested that the autoantibodies (autoAbs) against muscle acetylcholine receptor (AChR) of myasthenia gravis (MG) patients are the main pathogenic factor in MG; however, this belief has not yet been confirmed with direct observations. Although animals immunized with AChR or inj...

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Detalles Bibliográficos
Autores principales: Kordas, Gregory, Lagoumintzis, George, Sideris, Sotirios, Poulas, Konstantinos, Tzartos, Socrates J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4178151/
https://www.ncbi.nlm.nih.gov/pubmed/25259739
http://dx.doi.org/10.1371/journal.pone.0108327