A New IRAK-M-Mediated Mechanism Implicated in the Anti-Inflammatory Effect of Nicotine via α7 Nicotinic Receptors in Human Macrophages

Nicotine stimulation of α7 nicotinic acetylcholine receptor (α7 nAChR) powerfully inhibits pro-inflammatory cytokine production in lipopolysaccharide (LPS)-stimulated macrophages and in experimental models of endotoxemia. A signaling pathway downstream from the α7 nAChRs, which involves the collabor...

Descripción completa

Detalles Bibliográficos
Autores principales: Maldifassi, Maria C., Atienza, Gema, Arnalich, Francisco, López-Collazo, Eduardo, Cedillo, Jose L., Martín-Sánchez, Carolina, Bordas, Anna, Renart, Jaime, Montiel, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4178160/
https://www.ncbi.nlm.nih.gov/pubmed/25259522
http://dx.doi.org/10.1371/journal.pone.0108397

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4178160/
https://www.ncbi.nlm.nih.gov/pubmed/25259522
http://dx.doi.org/10.1371/journal.pone.0108397

Ejemplares similares