Cargando…
A New IRAK-M-Mediated Mechanism Implicated in the Anti-Inflammatory Effect of Nicotine via α7 Nicotinic Receptors in Human Macrophages
Nicotine stimulation of α7 nicotinic acetylcholine receptor (α7 nAChR) powerfully inhibits pro-inflammatory cytokine production in lipopolysaccharide (LPS)-stimulated macrophages and in experimental models of endotoxemia. A signaling pathway downstream from the α7 nAChRs, which involves the collabor...
Autores principales: | Maldifassi, Maria C., Atienza, Gema, Arnalich, Francisco, López-Collazo, Eduardo, Cedillo, Jose L., Martín-Sánchez, Carolina, Bordas, Anna, Renart, Jaime, Montiel, Carmen |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4178160/ https://www.ncbi.nlm.nih.gov/pubmed/25259522 http://dx.doi.org/10.1371/journal.pone.0108397 |
Ejemplares similares
-
The human-specific duplicated α7 gene inhibits the ancestral α7, negatively regulating nicotinic acetylcholine receptor-mediated transmitter release
por: Martín-Sánchez, Carolina, et al.
Publicado: (2021) -
Expression patterns for nicotinic acetylcholine receptor subunit genes in smoking-related lung cancers
por: Bordas, Anna, et al.
Publicado: (2017) -
Plasma levels of mitochondrial and nuclear DNA in patients with massive pulmonary embolism in the emergency department: a prospective cohort study
por: Arnalich, Francisco, et al.
Publicado: (2013) -
Possible role of the α7 nicotinic receptors in mediating nicotine’s effect on developing lung – implications in unexplained human perinatal death
por: Lavezzi, Anna M, et al.
Publicado: (2014) -
Contribution of the α5 nAChR Subunit and α5SNP to Nicotine-Induced Proliferation and Migration of Human Cancer Cells
por: Papapostolou, Irida, et al.
Publicado: (2023)