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Molecular Determinants of Agonist Selectivity in Glutamate-Gated Chloride Channels Which Likely Explain the Agonist Selectivity of the Vertebrate Glycine and GABA(A)-ρ Receptors

Orthologous Cys-loop glutamate-gated chloride channels (GluClR’s) have been cloned and described electrophysiologically and pharmacologically in arthropods and nematodes (both members of the invertebrate ecdysozoan superphylum). Recently, GluClR’s from Aplysia californica (a mollusc from the lophotr...

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Detalles Bibliográficos
Autores principales: Blarre, Thomas, Bertrand, Hugues-Olivier, Acher, Francine C., Kehoe, JacSue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4178172/
https://www.ncbi.nlm.nih.gov/pubmed/25259865
http://dx.doi.org/10.1371/journal.pone.0108458