Insulin Resistance Induced by Hyperinsulinemia Coincides with a Persistent Alteration at the Insulin Receptor Tyrosine Kinase Domain

Insulin resistance, the diminished response of target tissues to insulin, is associated with the metabolic syndrome and a predisposition towards diabetes in a growing proportion of the worldwide population. Under insulin resistant states, the cellular response of the insulin signaling pathway is dim...

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Detalles Bibliográficos
Autores principales: Catalano, Karyn J., Maddux, Betty A., Szary, Jaroslaw, Youngren, Jack F., Goldfine, Ira D., Schaufele, Fred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4178179/
https://www.ncbi.nlm.nih.gov/pubmed/25259572
http://dx.doi.org/10.1371/journal.pone.0108693

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4178179/
https://www.ncbi.nlm.nih.gov/pubmed/25259572
http://dx.doi.org/10.1371/journal.pone.0108693

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