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Melatonin Reverses Fas, E2F-1 and Endoplasmic Reticulum Stress Mediated Apoptosis and Dysregulation of Autophagy Induced by the Herbicide Atrazine in Murine Splenocytes

Exposure to the herbicide Atrazine (ATR) can cause immunotoxicity, apart from other adverse consequences for animal and human health. We aimed at elucidating the apoptotic mechanisms involved in immunotoxicity of ATR and their attenuation by Melatonin (MEL). Young Swiss mice were divided into contro...

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Detalles Bibliográficos
Autores principales: Sharma, Shweta, Sarkar, Jayanta, Haldar, Chandana, Sinha, Sudhir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4178181/
https://www.ncbi.nlm.nih.gov/pubmed/25259610
http://dx.doi.org/10.1371/journal.pone.0108602