The metabolic demands of cancer cells are coupled to their size and protein synthesis rates

BACKGROUND: Although cells require nutrients to proliferate, most nutrient exchange rates of the NCI60 panel of cancer cell lines correlate poorly with their proliferation rate. Here, we provide evidence indicating that this inconsistency is rooted in the variability of cell size. RESULTS: We integr...

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Detalles Bibliográficos
Autores principales: Dolfi, Sonia C, Chan, Leo Li-Ying, Qiu, Jean, Tedeschi, Philip M, Bertino, Joseph R, Hirshfield, Kim M, Oltvai, Zoltán N, Vazquez, Alexei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4178206/
https://www.ncbi.nlm.nih.gov/pubmed/24279929
http://dx.doi.org/10.1186/2049-3002-1-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4178206/
https://www.ncbi.nlm.nih.gov/pubmed/24279929
http://dx.doi.org/10.1186/2049-3002-1-20

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