Expression and phosphorylation of the AS160_v2 splice variant supports GLUT4 activation and the Warburg effect in multiple myeloma

BACKGROUND: Multiple myeloma (MM) is a fatal plasma cell malignancy exhibiting enhanced glucose consumption associated with an aerobic glycolytic phenotype (i.e., the Warburg effect). We have previously demonstrated that myeloma cells exhibit constitutive plasma membrane (PM) localization of GLUT4,...

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Detalles Bibliográficos
Autores principales: Cheng, Javelin C, McBrayer, Samuel K, Coarfa, Cristian, Dalva-Aydemir, Sevim, Gunaratne, Preethi H, Carpten, John D, Keats, Jonathan K, Rosen, Steven T, Shanmugam, Mala
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4178207/
https://www.ncbi.nlm.nih.gov/pubmed/24280290
http://dx.doi.org/10.1186/2049-3002-1-14

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4178207/
https://www.ncbi.nlm.nih.gov/pubmed/24280290
http://dx.doi.org/10.1186/2049-3002-1-14

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